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Table 3 Outcomes of interest: pairwise meta-analysis of laparoscopic vs open

From: Alternative treatments to treat perforated peptic ulcer: a systematic review and network meta-analysis of randomized controlled trials

Outcomes of interest

Number of studies and patients

(%; events/total)

Statistical method, estimated effect, 95% CI

p-value

I2 (%)

Return to diet

5, 378

MD = − 0.50 (− 1.35,0.35) (RE)

0.25

66

Postoperative pain

6, 479

MD = − 1.21 (− 2.09,—0.33) (RE)

0.007

94

Reoperations

4, 333

(4; 7/169 vs. 2; 3/164)

OR = 1.93 (0.57, 6.50) (FE)

0.08

43

Surgical Site Infections

6, 479

(2; 5/242 vs. 8.5; 20/237)

OR = 0.28 (0.11, 0.74) (FE)

0.01

0

Mortality

5, 434

(3; 6/221 vs. 4; 9/213)

OR = 0.60 (0.20, 1.78) (RE)

0.08

28

  1. MD mean difference; OR Odds ratio; FE fixed-effects model; RE random-effects; p-values highlighted in bold favor laparoscopy