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Table 3 Diagnostic criteria used

From: Diagnostic value of the appendicitis inflammatory response (AIR) score. A systematic review and meta-analysis

Reference

Diag

Follow up

Minimum histopathology criteria

Advanced app definitions

[16]

HP

1 month chart

Transmural inflammation

30 gangrenous or perforated

[17]

HP

6 month chart

Transmural inflammation

68 gangrenous or perforated

[18]

HP

30d chart

Transmural neutrophil infiltration

724 gangrenous or perforated or abscess

[19]

HP

N/A

Unclear

Unclear

[20]

HP

30d chart

Unclear

Unclear number gangrenous or perforated

[21]

HP

N/A

Unclear

Unclear

[22]

HP

N/A

Unclear

Unclear

[23]

HP

"Routine"

Muscularis propria neutrophil infiltration

92 gangrenous/perforated + 10 abscess

[24]

HP

2 weeks

Transmural neutrophil infiltration

Unclear

[25]

HP

N/A

Muscularis propria neutrophil infiltration

57 gangrenous + 38 perforated

[26]

HP/CT

Radiology or 3 month chart

Unclear

78 perforated + 4 abscess

[27]

HP

"Routine"

Muscularis propria neutrophil infiltration

28 unclear

[28, 29]

HP

1 month chart

Muscularis propria neutrophil infiltration

76 gangrenous/perforated/abscess

[30]

HP

N/A

Unclear

5 gangrenous + 3 perforated

[31]

HP

N/A

Muscularis propria neutrophil infiltration

13 perforated

[32]

HP

N/A

Unclear

17 gangrenous + 52 perforated

[33]

HP/MRI

Unclear

Unclear

2 abscess + 1 periapp phlegmon

[34]

HP

N/A

Unclear

Unclear

[35]

HP

Unclear

Transmural inflammation

16 gangrenous or perforated

[36]

HP

30d chart

Transmural inflammatory cell infiltration

41 gangrenous/perforated/abscess

[37]

HP

N/A

Unclear

Unclear

[38]

HP

Radiology and 2 weeks

Unclear

Unclear

[39]

HP

N/A

Unclear

23 perforated

[40]

HP

2 weeks chart

Transmural neutrophil infiltration

Unclear number perforated or abscess

[41]

HP

30 days

Transmural neutrophil infiltration

51 gangrenous/perforated/abscess

[42]

HP

N/A

Unclear

Unclear