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Table 1 Comparison of clinical characteristics of cholecystitis patients between different cohorts

From: An explainable predictive machine learning model of gangrenous cholecystitis based on clinical data: a retrospective single center study

 

level

No-gangrenous

Gangrenos

P

n

 

689

208

 

Sex(%)

Female

363

(52.7)

66

(31.7)

< 0.001

 

Male

326

(47.3)

142

(68.3)

 

Hypertension(%)

0

519

(75.3)

134

(64.4)

0.003

 

1

170

(24.7)

74

(35.6)

 

Diabetes(%)

0

591

(85.8)

170

(81.7)

0.188

 

1

98

(14.2)

38

(18.3)

 

CCD(%)

0

630

(91.4)

164

(78.8)

< 0.001

 

1

59

(8.6)

44

(21.2)

 

Anticoagulant

drugs(%)

0

669

(97.1)

186

(89.4)

< 0.001

 

1

20

(2.9)

22

(10.6)

 

General

Anesthesia

surgery(%)

0

437

(63.4)

126

(60.6)

0.507

 

1

252

(36.6)

82

(39.4)

 

Hypokalemia

Or hyponatremia(%)

0

604

(87.7)

100

(48.1)

< 0.001

 

1

85

(12.3)

108

(51.9)

 

Age,

median[IQR], year

 

56.00

[45.00, 65.00]

64.00

[55.00, 71.00]

< 0.001

WBC,

median[IQR], 10^9/L

 

6.82

[5.30, 9.21]

13.49

[10.13, 17.53]

< 0.001

NEU,

median[IQR], 10^9/L

 

4.32

[2.99, 7.11]

11.95

[8.36, 15.39]

< 0.001

LYM,

median[IQR], 10^9/L

 

1.59

[1.16, 2.05]

0.98

[0.71, 1.30]

< 0.001

NLR,

median[IQR]

 

2.56

[1.67, 5.27]

13.01

[7.21, 18.70]

< 0.001

PLT,

median[IQR], 10^9/L

 

231.00

[190.50, 274.00]

204.50

[161.75, 253.00]

< 0.001

PLR,

median[IQR]

 

148.86

[112.11, 196.67]

208.76

[148.75, 288.90]

< 0.001

ALT,

median[IQR], U/L

 

26.92

[18.00, 44.90]

31.15

[22.08, 56.15]

0.800

AST,

median[IQR], U/L

 

23.80

[18.62, 33.20]

29.20

[21.08, 45.23]

0.490

GGT,

median[IQR], U/L

 

29.70

[18.00, 76.78]

47.05

[26.00, 125.27]

0.055

Total bilirubin

median[IQR], µmol/L

 

15.28

[11.07, 22.40]

24.30

[16.13, 37.00]

< 0.001

D-dimer

median[IQR], ug/mL

 

0.54

[0.39, 0.77]

1.02

[0.66, 1.65]

< 0.001

Fibrinogen,

median[IQR], ug/mL

 

3.71

[3.12, 4.52]

5.61

[4.28, 7.24]

< 0.001

BMI,

median[IQR], kg/m2

 

24.80

[22.86, 27.68]

25.72

[23.44, 27.77]

0.060

Temperature,

median[IQR],℃

 

36.40

[36.10, 36.50]

36.50

[36.20, 36.90]

< 0.001

Heart rate,

median[IQR], bpm

 

78.00

[72.00, 85.00]

82.00

[73.00, 96.00]

< 0.001

Operation time,

median[IQR], min

 

75.00

[55.00, 100.00]

110.00

[80.00, 150.75]

< 0.001

Intraoperative

Bloodloss,

median[IQR], mL

 

10.00

[5.00, 20.00]

30.00

[10.00, 50.00]

< 0.001

Length of

Stay,

median[IQR], day

 

7.00

[5.00, 9.00]

8.00

[6.00, 10.00]

< 0.001

Gallbladder

Length,

median[IQR], cm

 

7.80

[6.00, 8.30]

8.90

[7.80, 10.00]

< 0.001

Gallbladder width,

median[IQR], cm

 

3.30

[2.40, 4.00]

3.90

[3.30, 4.50]

< 0.001

Gallbladder wallness,

median[IQR], cm

 

0.35

[0.30, 0.50]

0.50

[0.40, 0.60]

< 0.001

  1. CCD: Cardio cerebrovascular diseases