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Table 5 Predictors for SSI after emergency laparotomy at 30 days post op

From: Prophylactic PICO dressing shortens wound dressing requirements post emergency laparotomy (EL-PICO trial)

Variable

No SSI (N = 87)

N (%)

SSI (N = 9)

N (%)

Univariate analysis

(N = 96)

Multivariate analysis

(N = 96)

OR (95% CI)

P value

OR (95% CI)

P value

Age

      

< 65 years old

38 (43.7)

7 (77.8)

4.513 (0.886–22.979)

0.070

  

≥ 65 years old

49 (56.3)

2 (22.2)

Reference

   

BMI

     

0.037

Underweight

9 (10.3)

1 (11.1)

5.11 (0.29–89.46)

0.264

4.92 (0.24–200.91)

0.301

Overweight

27 (31.0)

4 (44.4)

6.82 (0.72–64.16)

0.093

8.17 (0.77–87.19)

0.082

Obese

5 (5.7)

3 (33.3)

27.60 (2.40–317.97)

0.008*

44.8 (3.25–615.84)

0.004

Normal

46 (52.9)

1 (11.1)

Reference

 

Reference

 

History and comorbidities

      

Smoker#

11 (12.6)

0 (0)

0.00 (0.00–none)

0.999

  

DM#

14 (16.1)

2 (22.2)

0.68 (0.13–3.57)

0.640

  

History of active cancer#

12 (13.8)

2 (22.2)

0.56 (0.10–3.02)

0.500

  

Albumin

      

≤ 35

53 (60.9)

7 (77.8)

2.25 (0.44–11.45)

0.331

  

> 35

34 (39.1)

2 (22.2)

Reference

   

Treatment

      

Chemotherapy#

4 (4.6)

2 (22.2)

0.078 (0.01–0.66)

0.019

12.08 (1.35–107.93)

0.026

Radiotherapy#

5 (5.7)

0 (0)

0.00 (0.00–none)

0.999

  

Steroids#

4 (4.6)

1 (11.1)

0.23 (0.02–2.61)

0.237

  

Type of dressing

      

PICO

45 (51.7)

2 (22.2)

0.27 (0.05–1.36)

0.111

  

Conventional

42 (48.3)

7 (77.8)

Reference

   

Diagnosis

   

0.830

  

Benign obstruction

13 (14.9)

1(11.1)

0.15 (0.01–3.58)

0.244

  

Benign perforation ischemia

24 (27.6)

4 (44.4)

0.33 (0.02–4.60)

0.412

  

Malignant obstruction

6 (6.9)

1 (11.1)

0.33 (0.01–8.18)

0.501

  

Malignant perforation

33 (37.9)

2 (22.2)

0.12 (0.01–1.98)

0.139

  

Trauma

5 (5.7)

0 (0)

0.00 (0.00-none)

0.999

  

Haemorrhage

4 (4.6)

0 (0)

Reference

   
  1. #Reference = no/none; 95% CI, 95% confidence interval; BMI, body mass index; DM, diabetes; SSI, surgical site infection; %, percentage; N, number; OR, odd ratio
  2. aBinary logistic regression; P < 0.05 denotes statistical significance, presented in bold